Shigeru Taketani Selected Research

Hypoxia (Hypoxemia)

1/2015	Hypoxia Enhances Proliferation of Human Adipose-Derived Stem Cells via HIF-1ɑ Activation.
12/2007	Death-resistant and nonresistant malignant human cell lines under anoxia in vitro.
5/2002	A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis.

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Shigeru Taketani Research Topics

Disease

12	Neoplasms (Cancer) 11/2014 - 12/2005
8	Acute Erythroblastic Leukemia (Erythroleukemia) 01/2016 - 01/2002
6	Inflammation (Inflammations) 07/2017 - 04/2005
4	Erythropoietic Protoporphyria 02/2018 - 05/2002
4	Colonic Neoplasms (Colon Cancer) 09/2014 - 12/2003
3	Hypoxia (Hypoxemia) 01/2015 - 05/2002
3	Carcinoma (Carcinomatosis) 11/2011 - 05/2011
3	Neuroblastoma 04/2006 - 05/2002
2	Porphyrias (Porphyria) 12/2013 - 01/2006
2	Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency) 12/2013 - 01/2006
2	Adenocarcinoma 07/2008 - 05/2008
1	Liver Diseases (Liver Disease) 01/2022
1	Jaundice (Icterus) 01/2022
1	Anemia 01/2022
1	Bile Duct Diseases (Bile Duct Disease) 01/2022
1	Moyamoya Disease (Moya-Moya Disease) 01/2020
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 02/2018
1	Fibrosis (Cirrhosis) 12/2015
1	Hyperinsulinism (Hyperinsulinemia) 12/2015
1	Obesity 01/2015
1	Type 2 Diabetes Mellitus (MODY) 01/2015
1	Fatty Liver 01/2015
1	Non-alcoholic Fatty Liver Disease 01/2015
1	Insulin Resistance 01/2015
1	Harderoporphyria 12/2013
1	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2013
1	Cataract (Cataracts) 07/2013
1	Strongyloidiasis 01/2013
1	Erythropoietic Porphyria (Congenital Erythropoietic Porphyria) 01/2013
1	Conversion Disorder (Astasia Abasia) 11/2011
1	Colorectal Neoplasms (Colorectal Cancer) 07/2009
1	Bone Resorption 03/2009

Drug/Important Bio-Agent (IBA)

12	Heme (Haem)IBA 07/2017 - 04/2003
8	Ferrochelatase (Heme Synthetase)IBA 01/2013 - 05/2002
7	Proteins (Proteins, Gene)FDA Link 01/2015 - 05/2002
7	IronIBA 11/2014 - 04/2003
7	protoporphyrin IXIBA 11/2014 - 12/2005
6	Messenger RNA (mRNA)IBA 01/2015 - 04/2003
6	EnzymesIBA 12/2013 - 04/2003
5	Aminolevulinic Acid (Levulan)FDA Link 09/2014 - 12/2005
4	1-phenyl-3,3-dimethyltriazene (PDT)IBA 09/2014 - 12/2005
3	CytokinesIBA 12/2015 - 11/2011
3	Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)IBA 12/2013 - 01/2006
3	PorphyrinsIBA 12/2013 - 09/2011
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 11/2011 - 05/2011
2	BilirubinIBA 01/2022 - 01/2016
2	Small Interfering RNA (siRNA)IBA 01/2015 - 01/2013
2	ElementsIBA 01/2015 - 05/2002
2	Phosphotransferases (Kinase)IBA 01/2015 - 07/2009
2	FrataxinIBA 11/2014 - 01/2013
2	Oxidoreductases (Dehydrogenase)IBA 12/2013 - 07/2013
2	Amino Acids FDA Link 12/2013 - 05/2002
2	AcidsIBA 01/2013 - 01/2006
2	Complementary DNA (cDNA)IBA 07/2008 - 05/2002
2	Adenosine Triphosphate (ATP)IBA 12/2007 - 04/2003
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 03/2007 - 11/2005
2	succinylacetoneIBA 11/2004 - 02/2004
1	Ligases (Synthetase)IBA 01/2020
1	UbiquitinIBA 01/2020
1	Azacitidine (5 Azacytidine)FDA Link 02/2018
1	withaferin AIBA 01/2017
1	LipopolysaccharidesIBA 01/2017
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017
1	Insulin (Novolin)FDA Link 12/2015
1	GlycogenIBA 12/2015
1	Sirtuin 1IBA 01/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2015
1	ChromatinIBA 01/2015
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2015
1	oxidized low density lipoproteinIBA 01/2015
1	Triglycerides (Triacylglycerol)IBA 01/2015
1	AntioxidantsIBA 01/2015
1	gamma-Aminobutyric Acid (GABA)IBA 09/2014
1	Aminobutyrates (Aminobutyric Acid)IBA 09/2014
1	harderoporphyrinogenIBA 12/2013
1	protoporphyrinogen (protoporphyrinogen IX)IBA 12/2013
1	coproporphyrinogen IIIIBA 07/2013
1	Uroporphyrinogen III Synthetase (Uroporphyrinogen-III Synthase)IBA 01/2013
1	UroporphyrinogensIBA 01/2013
1	Ursolic AcidIBA 11/2011
1	InterleukinsIBA 09/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2011
1	cytotrienin AIBA 09/2011
1	Rifabutin (Ansamycin)FDA Link 05/2011
1	mycotrienin IIIBA 05/2011
1	Protein Kinase CIBA 10/2009
1	ZincIBA 10/2009
1	Hemin (Panhematin)FDA Link 10/2009
1	Transforming Growth Factor beta (TGF-beta)IBA 07/2009
1	Estrogens (Estrogen)FDA Link 03/2009
1	sialosyl-Tn antigenIBA 07/2008
1	MucinsIBA 07/2008
1	AntigensIBA 07/2008

Therapy/Procedure

5	Photochemotherapy (Photodynamic Therapy) 09/2014 - 12/2005
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2015 - 09/2006
2	Transplantation 01/2015 - 09/2006
1	Stem Cell Transplantation 01/2015
1	Ovariectomy (Oophorectomy) 03/2009
1	Therapeutics 12/2008